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Alexandre D T Costa Selected Research

mitochondrial K(ATP) channel

4/2009MitoKATP activity in healthy and ischemic hearts.
3/2007Sarcoplasmic ATP-sensitive potassium channel blocker HMR1098 protects the ischemic heart: implication of calcium, complex I, reactive oxygen species and mitochondrial ATP-sensitive potassium channel.
3/2007Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS.
7/2006Inhibition of cardiac contractility by 5-hydroxydecanoate and tetraphenylphosphonium ion: a possible role of mitoKATP in response to inotropic stress.
9/2003Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K(+) channel in cardiac function and cardioprotection.

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Alexandre D T Costa Research Topics

Disease

4Ischemia
03/2007 - 09/2003
2Reperfusion Injury
03/2007 - 09/2003
1Malaria
01/2019
1Chagas Disease (American Trypanosomiasis)
10/2017
1Necrosis
04/2009
1Infarction (Infarctions)
03/2007
1Heart Failure
07/2006
1Rupture
01/2006

Drug/Important Bio-Agent (IBA)

5mitochondrial K(ATP) channelIBA
04/2009 - 09/2003
1SolutionsIBA
01/2019
1DNA (Deoxyribonucleic Acid)IBA
01/2019
1Proteins (Proteins, Gene)FDA Link
10/2017
1Ouabain (G Strophanthin)IBA
03/2007
1CalciumIBA
03/2007
1KATP ChannelsIBA
03/2007
1Adenosine Triphosphate (ATP)IBA
03/2007
1src-Family KinasesIBA
03/2007
1Cytochromes c (Cytochrome c)IBA
01/2006
1Bepridil (Vascor)FDA Link
01/2006
1ValinomycinIBA
01/2006
1Potassium Channels (Potassium Channel)IBA
09/2003